02-07-2023  12:35 am   •   PDX and SEA Weather
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NORTHWEST NEWS

Arrest Made in Stolen Yacht Rescue, 'Goonies' Fish Incident

Oregon police called it a series of “really odd” events along the Pacific Northwest coast spanning 48 hours that concluded Friday night with the arrest of a Canadian man.

Portland Cop Fired for Leaking False Allegations Against City Commissioner Reinstated

Mayor Ted Wheeler fired Brian Hunzeker after he leaked a false complaint saying city Commissioner Jo Ann Hardesty had been involved in a hit-and-run crash.

Hundreds of Portland City Workers on Strike for Better Pay

Workers represented by the union Laborers’ Local 483 have been without a contract since June. Negotiations over a new four-year deal broke down in December

Washington State Gov. Inslee Tests Positive for COVID-19

He plans to continue working. Trudi Inslee, the first spouse, has tested negative.

NEWS BRIEFS

Allen Temple C.M.E. Church Announces Annual Unsung Heroes & Heroines Award Luncheon

The purpose of the award is to acknowledge and honor individuals and/or organizations who are unsung heroes/heroines who make a...

Bonamici Invites Portland Community College President to 2023 State of the Union

PCC recently received 0K to advance semiconductor, advanced manufacturing training ...

Market Features Work of Local Black-Owned Businesses for Black History Month

MESO Makers Market in Portland to feature the work of 40 local, Black-owned small businesses to celebrate Black History Month in...

The Seattle Public Library's Homework Help Program Expands to Eight Locations and Increases Hours

Homework Help, The Seattle Public Library’s free after school tutoring service, will add two locations and increase hours in...

County Seeks Community Needs Survey Responses From Residents

Clark County Community Services is asking residents who are low-income to complete a survey to help determine what resources and...

1 missing, 2 rescued from crab boat off Washington coast

RAYMOND, Wash. (AP) — A crew member remains missing and two others were rescued from crab boat that sank near Willapa Bay in southwest Washington on Sunday evening, according to the Coast Guard. The Coast Guard on Twitter posted a video and said a helicopter crew from Astoria,...

Proposed bill would pay incarcerated workers minimum wage

OLYMPIA, Wash. (AP) — A Washington state lawmaker who has spent time in prison wants the state to pay incarcerated workers minimum wage for doing their jobs. State Rep. Tarra Simmons, D-Bremerton, is sponsoring House Bill 1024, called the “Real Labor, Real Wages Act,” to raise...

Jones scores 18, Southern Illinois tops Missouri State 73-53

CARBONDALE, Ill. (AP) — Lance Jones' 18 points helped Southern Illinois defeat Missouri State 73-53 on Sunday. Jones also added four steals for the Salukis (18-7, 10-4 Missouri Valley Conference). Troy D'Amico shot 5 of 6 from the field and 4 for 4 from the line to add 15 points....

DeVries and Drake earn 85-82 2OT win over Valparaiso

VALPARAISO, Ind. (AP) — Tucker DeVries scored a career-high 32 points and grabbed 11 rebounds and Drake beat Valparaiso 85-82 in double overtime on Saturday night. Roman Penn scored 16 points and added 12 rebounds and six assists for the Bulldogs (19-6, 10-4 Missouri Valley...

OPINION

Updates That May Affect Your Tax Season

The IRS released a statement that taxpayers should brace themselves for small tax refunds due to no economic impact payments ...

Unaffordable Rental Costs Now Plague 44 Million People in Every State Economic Inequality Places Most Risk of Eviction on Blacks and the Poor

For the first time in more than two decades of research, every state now has renters who are nearing a financial breaking point in housing affordability. ...

The Beating and Murder of Mr. Tyre Nichols, A Black Man

Time to Abolish the Criminal Injustice System ...

It's Time to Irrigate the Fallow Ground of Minority Media Ownership

In 2023, one aspect of civil rights and racial justice that barely remains addressed is racial inclusion in media ownership. ...

AFRICAN AMERICANS IN THE NEWS

Arkansas Gov. Sanders to offer State of the Union rebuttal

LITTLE ROCK, Ark. (AP) — Arkansas Gov. Sarah Huckabee Sanders, once a White House press secretary for President Donald Trump, is set to return to the national stage when she delivers the GOP response to President Joe Biden’s State of the Union address. Sanders, 40, is giving the...

State of the Union? Congress doesn't fully reflect diversity

WASHINGTON (AP) — When lawmakers gather for President Joe Biden's State of the Union address, the Republican side of the aisle will look slightly different than it did a few years ago. Rather than row after row of white men in suits, the House Republican majority increasingly has...

Missouri governor denies clemency for man facing execution

ST. LOUIS (AP) — Missouri Gov. Mike Parson said Monday he will not grant clemency and halt the execution of Raheem Taylor, who faces lethal injection for the deaths of his girlfriend and her three children. Taylor, 58, is scheduled to be put to death Tuesday evening at the state...

ENTERTAINMENT

List of Grammy winners in top categories

LOS ANGELES (AP) — Winners Sunday in the top categories at the 65th Grammy Awards: — Album of the year: “Harry’s House,” Harry Styles — Record of the year: “About Damn Time,” Lizzo — Song of the year (songwriter’s award): “Just Like...

Viola Davis' Grammy win for audiobook makes her an EGOT

LOS ANGELES (AP) — Viola Davis has achieved EGOT status. The actor won a Grammy Award Sunday for best audio book, narration, and storytelling recording for her memoir “Finding Me.” “I just EGOT!” she shouted from the stage as she accepted the trophy, using the...

Grammys 2023 live updates: Latest news from red carpet, show

LOS ANGELES (AP) — Follow along for real-time, on-the-carpet and behind-the-scenes updates on the 2023 Grammy Awards from The Associated Press. Live updates — any times Pacific — are brought to you by AP journalists at the show in Los Angeles and around the country. ___ ...

U.S. & WORLD NEWS

The Grammys ended in controversy, again. Here’s what to know

NEW YORK (AP) — A night in music brimming with shocking upsets, historic wins, tributes for artists like the...

What to Watch: New political vibes this State of the Union

WASHINGTON (AP) — Look for new faces and fresh political dynamics as President Joe Biden delivers this year's...

Lucky player in Washington wins 7 million Powerball prize

DES MOINES, Iowa (AP) — Someone in Washington state overcame steep odds Monday night to win an estimated 7...

EU Parliament planning for possible Zelenksyy visit in days

BRUSSELS (AP) — The European Union's legislature was preparing plans Monday to host Volodymyr Zelenskyy should...

India's aircraft carriers key to Indo-Pacific strategy

NEW DELHI (AP) — India is preparing to relaunch its INS Vikramaditya aircraft carrier after a major refit, a...

Hong Kong transgender men win appeal over status change

HONG KONG (AP) — Hong Kong’s top court ruled Monday that full sex reassignment surgery should not be a...

By The Skanner News | The Skanner News

BOSTON (AP) — A blood test so sensitive that it can spot a single cancer cell lurking among a billion healthy ones is moving one step closer to being available at your doctor's office.

Boston scientists who invented the test and health care giant Johnson & Johnson will announce Monday that they are joining forces to bring it to market. Four big cancer centers also will start studies using the experimental test this year.

Stray cancer cells in the blood mean that a tumor has spread or is likely to, many doctors believe. A test that can capture such cells has the potential to transform care for many types of cancer, especially breast, prostate, colon and lung.

Initially, doctors want to use the test to try to predict what treatments would be best for each patient's tumor and find out quickly if they are working.

"This is like a liquid biopsy" that avoids painful tissue sampling and may give a better way to monitor patients than periodic imaging scans, said Dr. Daniel Haber, chief of Massachusetts General Hospital's cancer center and one of the test's inventors.

Ultimately, the test may offer a way to screen for cancer besides the mammograms, colonoscopies and other less-than-ideal methods used now.

"There's a lot of potential here, and that's why there's a lot of excitement," said Dr. Mark Kris, lung cancer chief at Memorial Sloan-Kettering Cancer Center in New York. He had no role in developing the test, but Sloan-Kettering is one of the sites that will study it this year.

Many people have their cancers diagnosed through needle biopsies. These often do not provide enough of a sample to determine what genes or pathways control a tumor's growth. Or the sample may no longer be available by the time the patient gets sent to a specialist to decide what treatment to prescribe.

Doctors typically give a drug or radiation treatment and then do a CT scan two months later to look for tumor shrinkage. Some patients only live long enough to try one or two treatments, so a test that can gauge success sooner, by looking at cancer cells in the blood, could give patients more options.

"If you could find out quickly, 'this drug is working, stay on it,' or 'this drug is not working, try something else,' that would be huge," Haber said.

The only test on the market now to find tumor cells in blood — CellSearch, made by J&J's Veridex unit — just gives a cell count. It doesn't capture whole cells that doctors can analyze to choose treatments.

Interest in trying to collect these cells soared in 2007, after Haber and his colleagues published a study of Mass General's test. It is far more powerful than CellSearch and traps cells intact. It requires only a couple of teaspoons of blood and can be done repeatedly to monitor treatment or determine why a drug has stopped working and what to try next.

"That's what got the scientific community's interest," Kris said. Doctors can give a drug one day and sample blood the next day to see if the circulating tumor cells are gone, he explained.

The test uses a microchip that resembles a lab slide covered in 78,000 tiny posts, like bristles on a hairbrush. The posts are coated with antibodies that bind to tumor cells. When blood is forced across the chip, cells ping off the posts like balls in a pinball machine. The cancer cells stick, and stains make them glow so researchers can count and capture them for study.

The test can find one cancer cell in a billion or more healthy cells, said Mehmet Toner, a Harvard University bioengineer who helped design it. Researchers know this because they spiked blood samples with cancer cells and then searched for them with the chip.

Studies of the chip have been published in the journals Nature, the New England Journal of Medicine and Science Translational Medicine. It is the most promising of several dozen that companies and universities are rushing to develop to capture circulating tumor cells, said Bob McCormack, technology chief for Veridex.

The agreement announced Monday will have Veridex and J&J's Ortho Biotech Oncology unit work to improve the microchip, including trying a cheaper plastic to make it practical for mass production. No price goal has been set, a company official said, but the current CellSearch test costs several hundred dollars.

The companies will start a research center at Mass General and will have rights to license the test from the hospital, which holds the patents.

In a separate effort, Mass General, Sloan-Kettering, University of Texas M.D. Anderson Cancer Center in Houston and Dana-Farber Cancer Institute in Boston will start using the test this year. They are one of the "dream teams" sharing a $15 million grant from the Stand Up to Cancer telethon, run by the American Association for Cancer Research.

Already, scientists have been surprised to find that more cancer patients harbor these stray cells than has been believed. In one study, the test was used on men thought to have cancer confined to the prostate, "but we found these cells in two-thirds of patients," Toner said.

This might mean that cancer cells enter the blood soon after a tumor starts, or that more cancers have already spread but are unseen by doctors.

Or it could mean something else entirely, because researchers have much to learn about these cells, said Dr. Minetta Liu, a breast cancer specialist at Georgetown University's Lombardi Comprehensive Cancer Center. She led a session on them at the recent San Antonio Breast Cancer Symposium and has been a paid speaker for Veridex. She hopes the cells will someday aid cancer screening.

"The dream is, a woman comes in for her mammogram and gets a tube of blood drawn," so doctors can look for cancer cells in her blood as well as tumors on the imaging exam, she said.

That's still far off, but Mass General's test already is letting doctors monitor patients without painful biopsies. Like Greg Vrettos, who suffered a collapsed lung from a biopsy in 2004, when he was diagnosed with lung cancer.

"It had spread to both lungs and they couldn't operate," said Vrettos, 63, a nonsmoker and retired electrical engineer from Durham, N.H. Tests from the biopsy showed that he was a good candidate for the drug Iressa, which he has taken ever since. He goes to Boston every three months for CT scans and the blood test.

"They could look at the number of cancer cells and see that it dropped over time. It corresponded with what the scans were showing," Vrettos said of doctors looking at his blood tests.

The test also showed when he had a setback last January and needed to have his treatment adjusted.

"I think it's going to be revolutionary," he said of the test.

 

MLK Breakfast 2023

Photos from The Skanner Foundation's 37th Annual Martin Luther King, Jr. Breakfast.